Oxford/AstraZeneca Covid Vaccine 'Dose Error' Explained

On Monday, the world heard how the UK's Covid vaccine - from AstraZeneca and Oxford University - was highly effective in advanced trials.

It gave hope of another new jab to fight the pandemic that should be cheaper and easier to distribute than the Pfizer/BioNTech and Moderna mRNA vaccines that announced similarly impressive results just days before.

But after the jubilation, some negative press has followed.

On Thursday, multiple news outlets in the UK and US reported that there were questions over the data. They weren't about safety, but rather how effective the jab is.

The questions centre around efficacy levels.
Three were reported from the trial - an overall efficacy of 70%, a lower one of 62% and a high of 90%.

That's because different doses of the vaccine were mistakenly used in the trial. Some volunteers were given shots half the planned strength, in error. Yet that "wrong" dose turned out to be a winner.

What does that mean?

Some of the shots were weaker than they were designed to be, containing much less of the ingredient that is meant to give a person immunity.

The jab is actually two shots, with the second given a month after the first as a booster.

While most of the volunteers in the trial got the correct dose for both of their two shots, some didn't.

Regulators were told about the error early on and they agreed that the trial could continue and more volunteers could be immunised.

The error had no effect on vaccine safety.